5T5W

Structure of an affinity matured lambda-IFN/IFN-lambdaR1/IL-10Rbeta receptor complex

Summary for 5T5W

• Entry DOI: 10.2210/pdb5t5w/pdb
• Descriptor: Interleukin-10 receptor subunit beta, Interferon lambda receptor 1, Interferon lambda-3, ... (5 entities in total)
• Functional Keywords: receptor, cytokine, cytokine-cytokine receptor complex, cytokine/cytokine receptor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 70324.78

Authors

Mendoza, J.L.,Jude, K.M.,Garcia, K.C. (deposition date: 2016-08-31, release date: 2017-03-29, Last modification date: 2023-10-04)

• Primary citation: Mendoza, J.L.,Schneider, W.M.,Hoffmann, H.H.,Vercauteren, K.,Jude, K.M.,Xiong, A.,Moraga, I.,Horton, T.M.,Glenn, J.S.,de Jong, Y.P.,Rice, C.M.,Garcia, K.C.; The IFN-lambda-IFN-lambda R1-IL-10R beta Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity.; Immunity, 46:379-392, 2017; PubMed: 28329704; DOI: 10.1016/j.immuni.2017.02.017

Experimental method

X-RAY DIFFRACTION (2.847 Å)