5T0M

A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading

Summary for 5T0M

• Entry DOI: 10.2210/pdb5t0m/pdb
• Related: 5T0K
• Descriptor: Histone-lysine N-methyltransferase EHMT2, THR-LYS-GLN-THR-ALA-ARG-NLE-SER-THR-GLY, ZINC ION, ... (6 entities in total)
• Functional Keywords: histone methyltransferase, set domain, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 69725.70

Authors

Xu, K.,Tong, L. (deposition date: 2016-08-16, release date: 2016-10-05, Last modification date: 2023-11-15)

• Primary citation: Shan, C.M.,Wang, J.,Xu, K.,Chen, H.,Yue, J.X.,Andrews, S.,Moresco, J.J.,Yates, J.R.,Nagy, P.L.,Tong, L.,Jia, S.; A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading.; Elife, 5:-, 2016; PubMed: 27648579; DOI: 10.7554/eLife.17903

Experimental method

X-RAY DIFFRACTION (1.896 Å)