5T0A

Crystal Structure of Heparan Sulfate 6-O-Sulfotransferase with bound PAP and heptasaccharide substrate

Summary for 5T0A

• Entry DOI: 10.2210/pdb5t0a/pdb
• Related: 5T03 5T05
• Related PRD ID: PRD_900010
• Descriptor: maltose binding protein - heparan sulfate 6-O-sulfotransferase isoform 3 fusion protein, CHLORIDE ION, 2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, ... (11 entities in total)
• Functional Keywords: heparan sulfate, sulfotransferase, complex, transferase
• Biological source: Escherichia coli O157:H7; More
• Total number of polymer chains: 2
• Total formula weight: 164082.10

Authors

Pedersen, L.C.,Moon, A.F.,Krahn, J.M.,Liu, J. (deposition date: 2016-08-15, release date: 2017-02-01, Last modification date: 2020-07-29)

• Primary citation: Xu, Y.,Moon, A.F.,Xu, S.,Krahn, J.M.,Liu, J.,Pedersen, L.C.; Structure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases.; ACS Chem. Biol., 12:73-82, 2017; PubMed: 28103688; DOI: 10.1021/acschembio.6b00841

Experimental method

X-RAY DIFFRACTION (1.95 Å)