5SYF

High-resolution cryo-EM reconstruction of Taxol-stabilized microtubule

Summary for 5SYF

Entry DOI	10.2210/pdb5syf/pdb
Related	5SYC 5SYE 5SYG
EMDB information	5897 8320 8321 8322 8323
Descriptor	Tubulin alpha chain, Tubulin beta chain, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	taxol, microtubule, structural protein
Biological source	Sus scrofa (Pig) More
Total number of polymer chains	2
Total formula weight	98349.50
Authors	Kellogg, E.H.,Nogales, E. (deposition date: 2016-08-11, release date: 2017-02-01, Last modification date: 2024-03-06)
Primary citation	Kellogg, E.H.,Hejab, N.M.,Howes, S.,Northcote, P.,Miller, J.H.,Diaz, J.F.,Downing, K.H.,Nogales, E. Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures. J. Mol. Biol., 429:633-646, 2017 Cited by PubMed: 28104363 DOI: 10.1016/j.jmb.2017.01.001 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation