5SVK

Crystal structure of the ATP-gated human P2X3 ion channel in the ATP-bound, open state

Summary for 5SVK

• Entry DOI: 10.2210/pdb5svk/pdb
• Related: 5SVJ 5SVL 5SVM 5SVP 5SVQ 5SVR 5SVS 5SVT
• Related PRD ID: PRD_900001
• Descriptor: P2X purinoceptor 3, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... (7 entities in total)
• Functional Keywords: membrane protein, ion channel, open state
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 85738.13

Authors

Mansoor, S.E.,Lu, W.,Oosterheert, W.,Shekhar, M.,Tajkhorshid, E.,Gouaux, E. (deposition date: 2016-08-06, release date: 2016-09-28, Last modification date: 2020-07-29)

• Primary citation: Mansoor, S.E.,Lu, W.,Oosterheert, W.,Shekhar, M.,Tajkhorshid, E.,Gouaux, E.; X-ray structures define human P2X3 receptor gating cycle and antagonist action.; Nature, 538:66-71, 2016; PubMed: 27626375; DOI: 10.1038/nature19367

Experimental method

X-RAY DIFFRACTION (2.773 Å)