5SUY

Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from dimeric fraction

Summary for 5SUY

Entry DOI	10.2210/pdb5suy/pdb
Descriptor	Segment polarity protein dishevelled homolog DVL-2, SULFATE ION (3 entities in total)
Functional Keywords	dishevelled, dep domain, wnt signalling, signaling protein
Biological source	Homo sapiens (Human)
Cellular location	Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : O14641
Total number of polymer chains	4
Total formula weight	43673.63
Authors	Renko, M.,Gammons, M.V.,Bienz, M. (deposition date: 2016-08-04, release date: 2016-10-12, Last modification date: 2016-10-19)
Primary citation	Gammons, M.V.,Renko, M.,Johnson, C.M.,Rutherford, T.J.,Bienz, M. Wnt Signalosome Assembly by DEP Domain Swapping of Dishevelled. Mol.Cell, 64:92-104, 2016 Cited by PubMed: 27692984 DOI: 10.1016/j.molcel.2016.08.026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation