5PN0

PanDDA analysis group deposition -- Crystal Structure of JMJD2D after initial refinement with no ligand modelled (structure 194)

Summary for 5PN0

Entry DOI	10.2210/pdb5pn0/pdb
Group deposition	PanDDA analysis group deposition of models of ground state datasets (G_1002021)
Descriptor	Lysine-specific demethylase 4D, ZINC ION, NICKEL (II) ION, ... (8 entities in total)
Functional Keywords	pandda, sgc - diamond i04-1 fragment screening, jmj domain, epigenetics, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	43130.76
Authors	Pearce, N.M.,Krojer, T.,Talon, R.,Bradley, A.R.,Fairhead, M.,Sethi, R.,Wright, N.,MacLean, E.,Collins, P.,Brandao-Neto, J.,Douangamath, A.,Renjie, Z.,Dias, A.,Vollmar, M.,Ng, J.,Szykowska, A.,Burgess-Brown, N.,Brennan, P.E.,Cox, O.,Oppermann, U.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.,von Delft, F. (deposition date: 2017-02-07, release date: 2017-03-15, Last modification date: 2024-03-06)
Primary citation	Pearce, N.M.,Krojer, T.,Bradley, A.R.,Collins, P.,Nowak, R.P.,Talon, R.,Marsden, B.D.,Kelm, S.,Shi, J.,Deane, C.M.,von Delft, F. A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8:15123-15123, 2017 Cited by PubMed: 28436492 DOI: 10.1038/ncomms15123 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.14 Å)

Structure validation