5OW7

VDR complex

Summary for 5OW7

• Entry DOI: 10.2210/pdb5ow7/pdb
• Related: 2HC4 5MX7
• Descriptor: Vitamin D3 receptor A, Nuclear receptor coactivator 1, (3~{S})-3-[(1~{S},3~{a}~{S},4~{E},7~{a}~{S})-7~{a}-methyl-4-[(2~{Z})-2-[(5~{S})-2-methylidene-5-oxidanyl-cyclohexylidene]ethylidene]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-1-yl]-3-oxidanyl-~{N}-propan-2-yl-butanamide, ... (4 entities in total)
• Functional Keywords: nuclear receptor, complex, vitamin d receptor, transcription
• Biological source: Danio rerio (Zebrafish); More
• Cellular location: Nucleus : Q9PTN2 Q15788
• Total number of polymer chains: 2
• Total formula weight: 36252.35

Authors

Rochel, N.,Li, W. (deposition date: 2017-08-31, release date: 2018-02-07, Last modification date: 2024-01-17)

• Primary citation: Lin, Z.,Marepally, S.R.,Goh, E.S.Y.,Cheng, C.Y.S.,Janjetovic, Z.,Kim, T.K.,Miller, D.D.,Postlethwaite, A.E.,Slominski, A.T.,Tuckey, R.C.,Peluso-Iltis, C.,Rochel, N.,Li, W.; Investigation of 20S-hydroxyvitamin D3 analogs and their 1 alpha-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities.; Sci Rep, 8:1478-1478, 2018; PubMed: 29367669; DOI: 10.1038/s41598-018-19183-7

Experimental method

X-RAY DIFFRACTION (2.1 Å)