5NP0

Closed dimer of human ATM (Ataxia telangiectasia mutated)

Summary for 5NP0

• Entry DOI: 10.2210/pdb5np0/pdb
• EMDB information: 3669
• Descriptor: Serine-protein kinase ATM (1 entity in total)
• Functional Keywords: pikk, kinase, dna-repair, heat-repeats, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 704787.94

Authors

Baretic, D.,Pollard, H.K.,Fisher, D.I.,Johnson, C.M.,Santhanam, B.,Truman, C.M.,Kouba, T.,Fersht, A.R.,Phillips, C.,Williams, R.L. (deposition date: 2017-04-13, release date: 2017-05-17, Last modification date: 2019-12-11)

• Primary citation: Baretic, D.,Pollard, H.K.,Fisher, D.I.,Johnson, C.M.,Santhanam, B.,Truman, C.M.,Kouba, T.,Fersht, A.R.,Phillips, C.,Williams, R.L.; Structures of closed and open conformations of dimeric human ATM.; Sci Adv, 3:e1700933-e1700933, 2017; PubMed: 28508083; DOI: 10.1126/sciadv.1700933

Experimental method

ELECTRON MICROSCOPY (5.7 Å)