5NG3
Structure of inactive kinase RIP2K(K47R)
Summary for 5NG3
| Entry DOI | 10.2210/pdb5ng3/pdb |
| Descriptor | Receptor-interacting serine/threonine-protein kinase 2, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | rip2k, kinase, inactive state, helixc-out, transferase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 141633.21 |
| Authors | Pellegrini, E.,Cusack, S. (deposition date: 2017-03-16, release date: 2017-06-28, Last modification date: 2024-01-17) |
| Primary citation | Pellegrini, E.,Signor, L.,Singh, S.,Boeri Erba, E.,Cusack, S. Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation. PLoS ONE, 12:e0177161-e0177161, 2017 Cited by PubMed: 28545134DOI: 10.1371/journal.pone.0177161 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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