5NG2
Structure of RIP2K(D146N) with bound Staurosporine
Summary for 5NG2
| Entry DOI | 10.2210/pdb5ng2/pdb |
| Descriptor | Receptor-interacting serine/threonine-protein kinase 2, STAUROSPORINE, PHOSPHATE ION, ... (4 entities in total) |
| Functional Keywords | rip2k, kinase, inactive state, staurosporine, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 71124.82 |
| Authors | Pellegrini, E.,Cusack, S. (deposition date: 2017-03-16, release date: 2017-06-07, Last modification date: 2024-01-17) |
| Primary citation | Pellegrini, E.,Signor, L.,Singh, S.,Boeri Erba, E.,Cusack, S. Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation. PLoS ONE, 12:e0177161-e0177161, 2017 Cited by PubMed: 28545134DOI: 10.1371/journal.pone.0177161 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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