5NFB

Structure of Galectin-3 CRD in complex with compound 4

Summary for 5NFB

Entry DOI	10.2210/pdb5nfb/pdb
Related	5NF7 5NF9 5NFA
Descriptor	Galectin-3, ~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-2-acetamido-6-(hydroxymethyl)-5-[(2~{S},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-4-[(3-methoxyphenyl)methoxy]-3,5-bis(oxidanyl)oxan-2-yl]oxy-4-oxidanyl-oxan-3-yl]-3-methoxy-benzamide (3 entities in total)
Functional Keywords	galectin-3 crd, cation-pi interactions, sugar binding protein
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P17931
Total number of polymer chains	1
Total formula weight	20572.08
Authors	Ronin, C.,Atmanene, C.,Gautier, F.M.,Djedaini Pilard, F.,Teletchea, S.,Ciesielski, F.,Vivat Hannah, V.,Grandjean, C. (deposition date: 2017-03-13, release date: 2017-06-21, Last modification date: 2024-01-17)
Primary citation	Atmanene, C.,Ronin, C.,Teletchea, S.,Gautier, F.M.,Djedaini-Pilard, F.,Ciesielski, F.,Vivat, V.,Grandjean, C. Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3. Biochem. Biophys. Res. Commun., 489:281-286, 2017 Cited by PubMed: 28554839 DOI: 10.1016/j.bbrc.2017.05.150 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation