5N75
14-3-3 sigma in complex with TAZ pS89 peptide
Summary for 5N75
Entry DOI | 10.2210/pdb5n75/pdb |
Descriptor | 14-3-3 protein sigma, WW domain-containing transcription regulator protein 1, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | 14-3-3, taz, yap, signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: P31947 |
Total number of polymer chains | 2 |
Total formula weight | 27873.31 |
Authors | Sijbesma, E.,Leysen, S.,Ottmann, C. (deposition date: 2017-02-19, release date: 2017-07-19, Last modification date: 2024-01-17) |
Primary citation | Sijbesma, E.,Skora, L.,Leysen, S.,Brunsveld, L.,Koch, U.,Nussbaumer, P.,Jahnke, W.,Ottmann, C. Identification of Two Secondary Ligand Binding Sites in 14-3-3 Proteins Using Fragment Screening. Biochemistry, 56:3972-3982, 2017 Cited by PubMed: 28681606DOI: 10.1021/acs.biochem.7b00153 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.803 Å) |
Structure validation
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