5N06

Crystal structure of Tie1 Fibronectin-like domain 3

Summary for 5N06

Entry DOI	10.2210/pdb5n06/pdb
Descriptor	Tyrosine-protein kinase receptor Tie-1 (2 entities in total)
Functional Keywords	receptor, fibronectin-like domains, heterodimerization, signaling protein
Biological source	Homo sapiens (Human)
Cellular location	Cell membrane ; Single-pass type I membrane protein : P35590
Total number of polymer chains	2
Total formula weight	28133.81
Authors	Leppanen, V.-M.,Saharinen, P.,Alitalo, K. (deposition date: 2017-02-02, release date: 2017-04-26, Last modification date: 2017-05-03)
Primary citation	Leppanen, V.M.,Saharinen, P.,Alitalo, K. Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization. Proc. Natl. Acad. Sci. U.S.A., 114:4376-4381, 2017 Cited by PubMed: 28396439 DOI: 10.1073/pnas.1616166114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.501 Å)

Structure validation