5MY6

Crystal structure of a HER2-Nb complex

Summary for 5MY6

• Entry DOI: 10.2210/pdb5my6/pdb
• Descriptor: Receptor tyrosine-protein kinase erbB-2, Nanobody 2Rs15d, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: nanobody, her2, egfr family, radio-labeling, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 82036.73

Authors

Sterckx, Y.G.-J.,D'Huyvetter, M.,Devoogdt, N. (deposition date: 2017-01-25, release date: 2017-08-09, Last modification date: 2024-01-17)

• Primary citation: D'Huyvetter, M.,De Vos, J.,Xavier, C.,Pruszynski, M.,Sterckx, Y.G.J.,Massa, S.,Raes, G.,Caveliers, V.,Zalutsky, M.R.,Lahoutte, T.,Devoogdt, N.; (131)I-labeled Anti-HER2 Camelid sdAb as a Theranostic Tool in Cancer Treatment.; Clin. Cancer Res., 23:6616-6628, 2017; PubMed: 28751451; DOI: 10.1158/1078-0432.CCR-17-0310

Experimental method

X-RAY DIFFRACTION (2.246 Å)