5MTN
Monobody Mb(Lck_1) bound to Lck-Sh2
Summary for 5MTN
| Entry DOI | 10.2210/pdb5mtn/pdb |
| Descriptor | Tyrosine-protein kinase Lck, Monobody Mb(Lck_1), SULFATE ION (3 entities in total) |
| Functional Keywords | src homology 2, monobodies, directed evolution, transferase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 23485.02 |
| Authors | Pojer, F.,Kukenshoner, T.,Koide, S.,Hantschel, O. (deposition date: 2017-01-10, release date: 2017-04-05, Last modification date: 2019-10-16) |
| Primary citation | Kukenshoner, T.,Schmit, N.E.,Bouda, E.,Sha, F.,Pojer, F.,Koide, A.,Seeliger, M.,Koide, S.,Hantschel, O. Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies. J. Mol. Biol., 429:1364-1380, 2017 Cited by PubMed: 28347651DOI: 10.1016/j.jmb.2017.03.023 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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