5MSA

Crystal structure of human carbonic anhydrase isozyme XII with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide

Summary for 5MSA

• Entry DOI: 10.2210/pdb5msa/pdb
• Related: 5LLC 5LLE 5LLG 5LLH 5LLN 5LLO 5LLP
• Descriptor: Carbonic anhydrase 12, ZINC ION, 2,3,5,6-tetrafluoro-4-(propylsulfanyl)benzenesulfonamide, ... (7 entities in total)
• Functional Keywords: drug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase
• Biological source: Homo sapiens (Human)
• Cellular location: Membrane; Single-pass type I membrane protein: O43570
• Total number of polymer chains: 4
• Total formula weight: 122889.76

Authors

Smirnov, A.,Manakova, E.,Grazulis, S. (deposition date: 2017-01-02, release date: 2018-01-17, Last modification date: 2024-01-17)

• Primary citation: Smirnov, A.,Manakova, E.,Grazulis, S.,Matulis, D.,Dudutiene, V.; Crystal structure of human carbonic anhydrase isozyme XII with 2,3,5,6-Tetrafluoro-4-(propylthio)benzenesulfonamide; To be published,

Experimental method

X-RAY DIFFRACTION (1.2 Å)