5MCW

New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LWC2)

Summary for 5MCW

Entry DOI	10.2210/pdb5mcw/pdb
Related	3KZ8 5MCT 5MCU 5MCV 5MF7 5MG7 6FJ5
Descriptor	Cellular tumor antigen p53, DNA, ZINC ION, ... (5 entities in total)
Functional Keywords	transcription, p53, transcription factor, dna binding, dna recognition, watson-crick base-pairing, inosine, 5-methylcytosine, transcription regulation, apoptosis, biological rhythms, cell cycle, nucleus, tumor suppressor, antigen ny-co-13, phosphoprotein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	51643.17
Authors	Golovenko, D.,Rozenberg, H.,Shakked, Z. (deposition date: 2016-11-10, release date: 2018-06-13, Last modification date: 2024-01-17)
Primary citation	Golovenko, D.,Brauning, B.,Vyas, P.,Haran, T.E.,Rozenberg, H.,Shakked, Z. New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26:1237-1250.e6, 2018 Cited by PubMed: 30057026 DOI: 10.1016/j.str.2018.06.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.897 Å)

Structure validation