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5M35

The molecular tweezer CLR01 stabilizes a disordered protein-protein interface

Replaces:  5JIT
Summary for 5M35
Entry DOI10.2210/pdb5m35/pdb
Related3UX0 5EWZ 5EXA
Descriptor14-3-3 protein zeta/delta, M-phase inducer phosphatase 3, GLYCEROL, ... (6 entities in total)
Functional Keywordsstabilization, 14-3-3, disordered ppi interface, cdc25c, hydrolase
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight54989.76
Authors
Bier, D.,Ottmann, C. (deposition date: 2016-10-14, release date: 2017-11-15, Last modification date: 2024-01-17)
Primary citationBier, D.,Mittal, S.,Bravo-Rodriguez, K.,Sowislok, A.,Guillory, X.,Briels, J.,Heid, C.,Bartel, M.,Wettig, B.,Brunsveld, L.,Sanchez-Garcia, E.,Schrader, T.,Ottmann, C.
The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface.
J. Am. Chem. Soc., 139:16256-16263, 2017
Cited by
PubMed: 29039919
DOI: 10.1021/jacs.7b07939
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.38 Å)
Structure validation

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