5M0R

Cryo-EM reconstruction of the maedi-visna virus (MVV) strand transfer complex

Summary for 5M0R

Entry DOI	10.2210/pdb5m0r/pdb
EMDB information	4139
Descriptor	integrase, vDNA, non-transfered strand, vDNA-tDNA, transferred strand, joined to a model tDNA, ... (4 entities in total)
Functional Keywords	retrovirus, lentivirus, integrase, dna-binding, zn-binding, rnaseh fold, hydrolase
Biological source	Maedi visna virus (strain KV1772) (MVV) More
Total number of polymer chains	22
Total formula weight	575736.43
Authors	Pye, V.E.,Ballandras-Colas, A.,Maskell, D.,Locke, J.,Kotecha, A.,Costa, A.,Cherepanov, P. (deposition date: 2016-10-05, release date: 2017-01-18, Last modification date: 2018-11-21)
Primary citation	Ballandras-Colas, A.,Maskell, D.P.,Serrao, E.,Locke, J.,Swuec, P.,Jonsson, S.R.,Kotecha, A.,Cook, N.J.,Pye, V.E.,Taylor, I.A.,Andresdottir, V.,Engelman, A.N.,Costa, A.,Cherepanov, P. A supramolecular assembly mediates lentiviral DNA integration. Science, 355:93-95, 2017 Cited by PubMed: 28059770 DOI: 10.1126/science.aah7002 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (8.2 Å)

Structure validation