5LRV

Structure of Cezanne/OTUD7B OTU domain bound to Lys11-linked diubiquitin

Summary for 5LRV

Entry DOI	10.2210/pdb5lrv/pdb
Descriptor	OTU domain-containing protein 7B, Polyubiquitin-B, PHOSPHATE ION, ... (6 entities in total)
Functional Keywords	hydrolase, protease, deubiquitinase, otu domain
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm : Q6GQQ9 Ubiquitin: Cytoplasm : P0CG47 P0CG47
Total number of polymer chains	3
Total formula weight	53976.38
Authors	Mevissen, T.E.T.,Kulathu, Y.,Mulder, M.P.C.,Geurink, P.P.,Maslen, S.L.,Gersch, M.,Elliott, P.R.,Burke, J.E.,van Tol, B.D.M.,Akutsu, M.,El Oualid, F.,Kawasaki, M.,Freund, S.M.V.,Ovaa, H.,Komander, D. (deposition date: 2016-08-22, release date: 2016-10-19, Last modification date: 2023-11-15)
Primary citation	Mevissen, T.E.,Kulathu, Y.,Mulder, M.P.,Geurink, P.P.,Maslen, S.L.,Gersch, M.,Elliott, P.R.,Burke, J.E.,van Tol, B.D.,Akutsu, M.,El Oualid, F.,Kawasaki, M.,Freund, S.M.,Ovaa, H.,Komander, D. Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature, 538:402-405, 2016 Cited by PubMed: 27732584 DOI: 10.1038/nature19836 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation