5LLK

Crystal structure of human alpha-dystroglycan

Summary for 5LLK

Entry DOI	10.2210/pdb5llk/pdb
Descriptor	Dystroglycan, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	dystroglycan, extraellular matrix adhesion, cell adhesion
Biological source	Homo sapiens (Human)
Cellular location	Alpha-dystroglycan: Secreted, extracellular space. Beta-dystroglycan: Cell membrane; Single- pass type I membrane protein: Q14118
Total number of polymer chains	1
Total formula weight	28678.59
Authors	Covaceuszach, S.,Cassetta, A.,Lamba, D.,Brancaccio, A.,Bozzi, M.,Sciandra, F.,Bigotti, M.G.,Konarev, P.V. (deposition date: 2016-07-27, release date: 2017-07-12, Last modification date: 2024-01-10)
Primary citation	Covaceuszach, S.,Bozzi, M.,Bigotti, M.G.,Sciandra, F.,Konarev, P.V.,Brancaccio, A.,Cassetta, A. Structural flexibility of human alpha-dystroglycan. FEBS Open Bio, 7:1064-1077, 2017 Cited by PubMed: 28781947 DOI: 10.1002/2211-5463.12259 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation