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5LKS

Structure-function insights reveal the human ribosome as a cancer target for antibiotics

This is a non-PDB format compatible entry.
Summary for 5LKS
Entry DOI10.2210/pdb5lks/pdb
EMDB information4070
Descriptor28S ribosomal RNA, 60S ribosomal protein L7a, 60S ribosomal protein L9, ... (84 entities in total)
Functional Keywordscryoem, human ribosome, 80s, cycloheximide, ribosome
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains80
Total formula weight3818879.56
Authors
Myasnikov, A.G.,Natchiar, S.K.,Nebout, M.,Hazemann, I.,Imbert, V.,Khatter, H.,Peyron, J.-F.,Klaholz, B.P. (deposition date: 2016-07-23, release date: 2017-04-26, Last modification date: 2019-12-11)
Primary citationMyasnikov, A.G.,Kundhavai Natchiar, S.,Nebout, M.,Hazemann, I.,Imbert, V.,Khatter, H.,Peyron, J.F.,Klaholz, B.P.
Structure-function insights reveal the human ribosome as a cancer target for antibiotics.
Nat Commun, 7:12856-12856, 2016
Cited by
PubMed: 27665925
DOI: 10.1038/ncomms12856
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.6 Å)
Structure validation

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