5LEK

The Transcriptional Regulator PrfA-G145S mutant from Listeria Monocytogenes in complex with a 30-bp operator PrfA-box motif

Summary for 5LEK

• Entry DOI: 10.2210/pdb5lek/pdb
• Related: 2beo
• Descriptor: Listeriolysin regulatory protein, DNA (30-MER), ... (4 entities in total)
• Functional Keywords: transcription regulator, dna binding, activation, listeria monocytogenes, transcription
• Biological source: Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e); More
• Total number of polymer chains: 4
• Total formula weight: 73160.79

Authors

Hall, M.,Grundstrom, C.,Begum, A.,Lindberg, M.,Sauer, U.H.,Almqvist, F.,Johansson, J.,Sauer-Eriksson, A.E. (deposition date: 2016-06-29, release date: 2016-12-07, Last modification date: 2024-01-10)

• Primary citation: Hall, M.,Grundstrom, C.,Begum, A.,Lindberg, M.J.,Sauer, U.H.,Almqvist, F.,Johansson, J.,Sauer-Eriksson, A.E.; Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria.; Proc. Natl. Acad. Sci. U.S.A., 113:14733-14738, 2016; PubMed: 27930316; DOI: 10.1073/pnas.1614028114

Experimental method

X-RAY DIFFRACTION (2.8 Å)