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5L1K

PostInsertion complex of Human DNA Polymerase Eta bypassing an O6-Methyl-2'-deoxyguanosine : dC site

Summary for 5L1K
Entry DOI10.2210/pdb5l1k/pdb
Related5L1I 5L1J 5L1L
DescriptorDNA polymerase eta, DNA (5'-D(*CP*AP*TP*GP*(6OG)P*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*C)-3'), ... (7 entities in total)
Functional Keywordscatalytic domain, dna damage, dna polymerase, lesion bypass, o6-methyl-2'-deoxyguanosine, y-family polymerase, translesion dna synthesis (tls), dna binding protein., transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
More
Cellular locationNucleus : Q9Y253
Total number of polymer chains3
Total formula weight55328.62
Authors
Patra, A.,Egli, M. (deposition date: 2016-07-29, release date: 2016-10-05, Last modification date: 2023-10-04)
Primary citationPatra, A.,Zhang, Q.,Guengerich, F.P.,Egli, M.
Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase eta.
J.Biol.Chem., 291:24304-24313, 2016
Cited by
PubMed: 27694439
DOI: 10.1074/jbc.M116.755462
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.82 Å)
Structure validation

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