5L1F
AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor Perampanel
Summary for 5L1F
Entry DOI | 10.2210/pdb5l1f/pdb |
Related | 5L1B 5L1E 5L1G 5L1H |
Descriptor | Glutamate receptor 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile (3 entities in total) |
Functional Keywords | transporter, membrane protein, transport protein, transport protein-inhibitor complex, transport protein/inhibitor |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 4 |
Total formula weight | 361505.31 |
Authors | Yelshanskaya, M.V.,Singh, A.K.,Sampson, J.M.,Sobolevsky, A.I. (deposition date: 2016-07-29, release date: 2016-10-19, Last modification date: 2023-10-04) |
Primary citation | Yelshanskaya, M.V.,Singh, A.K.,Sampson, J.M.,Narangoda, C.,Kurnikova, M.,Sobolevsky, A.I. Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs. Neuron, 91:1305-1315, 2016 Cited by PubMed: 27618672DOI: 10.1016/j.neuron.2016.08.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4 Å) |
Structure validation
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