5KYB

Crystal structure of the apo-form of USP7 catalytic domain [V302K] mutant

Summary for 5KYB

• Entry DOI: 10.2210/pdb5kyb/pdb
• Related: 5KYC 5KYD 5KYE 5KYF
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 7, GLYCEROL (3 entities in total)
• Functional Keywords: usp7 catalytic domain, deubiquitinase, v302k mutant, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 81420.05

Authors

Rouge, L.,Ozen, A. (deposition date: 2016-07-21, release date: 2017-08-09, Last modification date: 2023-10-04)

• Primary citation: Ozen, A.,Rouge, L.,Bashore, C.,Hearn, B.R.,Skelton, N.J.,Dueber, E.C.; Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation.; Structure, 26:72-84.e7, 2018; PubMed: 29249604; DOI: 10.1016/j.str.2017.11.010

Experimental method

X-RAY DIFFRACTION (2.2 Å)