5KS7

Crystal structure of Listeria monocytogenes OpuCA CBS domain dimer in complex with cyclic-di-AMP

Summary for 5KS7

Entry DOI	10.2210/pdb5ks7/pdb
Related	5KS8
Descriptor	Carnitine transport ATP-binding protein OpuCA, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide (2 entities in total)
Functional Keywords	cbs domain, abc transporter, cyclic-di-amp, osmoregulation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Listeria monocytogenes
Total number of polymer chains	2
Total formula weight	29273.44
Authors	Choi, P.H.,Tong, L. (deposition date: 2016-07-07, release date: 2016-07-20, Last modification date: 2024-04-03)
Primary citation	Huynh, T.N.,Choi, P.H.,Sureka, K.,Ledvina, H.E.,Campillo, J.,Tong, L.,Woodward, J.J. Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC. Mol.Microbiol., 102:233-243, 2016 Cited by PubMed: 27378384 DOI: 10.1111/mmi.13456 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation