6ASZ

Chromodomain HP1 with Y24F mutation bound to histone H3 peptide containing trimethyl lysine

Replaces:  5KOG

Summary for 6ASZ

• Entry DOI: 10.2210/pdb6asz/pdb
• Descriptor: Heterochromatin protein 1, trimethyl lysine histone H3 tail peptide (3 entities in total)
• Functional Keywords: histone reader, transcription
• Biological source: Drosophila melanogaster (Fruit fly); More
• Total number of polymer chains: 2
• Total formula weight: 9304.33

Authors

Brustad, E.M.,Baril, S.A.,Waters, M.L. (deposition date: 2017-08-27, release date: 2017-12-06, Last modification date: 2023-10-04)

• Primary citation: Baril, S.A.,Koenig, A.L.,Krone, M.W.,Albanese, K.I.,He, C.Q.,Lee, G.Y.,Houk, K.N.,Waters, M.L.,Brustad, E.M.; Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis.; J. Am. Chem. Soc., 139:17253-17256, 2017; PubMed: 29111699; DOI: 10.1021/jacs.7b09223

Experimental method

X-RAY DIFFRACTION (1.518 Å)