5KNM

Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors

Summary for 5KNM

Entry DOI	10.2210/pdb5knm/pdb
Related	5IUE
Descriptor	cDNA FLJ39643 fis, clone SMINT2004023, highly similar to HLA class I histocompatibility antigen, alphachain F, Beta-2-microglobulin, Leukocyte immunoglobulin-like receptor subfamily B member 1, ... (5 entities in total)
Functional Keywords	mhc-ib, immune system, peptide binding protein, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	83362.59
Authors	Dulberger, C.L.,Adams, E.J. (deposition date: 2016-06-28, release date: 2017-06-14, Last modification date: 2023-09-27)
Primary citation	Dulberger, C.L.,McMurtrey, C.P.,Holzemer, A.,Neu, K.E.,Liu, V.,Steinbach, A.M.,Garcia-Beltran, W.F.,Sulak, M.,Jabri, B.,Lynch, V.J.,Altfeld, M.,Hildebrand, W.H.,Adams, E.J. Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors. Immunity, 46:1018-1029.e7, 2017 Cited by PubMed: 28636952 DOI: 10.1016/j.immuni.2017.06.002 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation