5KLR

Prototypical P4[R]cNLS

Summary for 5KLR

• Entry DOI: 10.2210/pdb5klr/pdb
• Related: 5KLT
• Descriptor: Importin subunit alpha-1, Prototypical P4[R]cNLS (3 entities in total)
• Functional Keywords: importin alpha, complex, nuclear localisation signal, protein transport-viral protein complex, protein transport/viral protein
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 56990.56

Authors

Smith, K.M.,Forwood, J.K. (deposition date: 2016-06-25, release date: 2016-07-27, Last modification date: 2023-09-27)

• Primary citation: Smith, K.M.,Di Antonio, V.,Bellucci, L.,Thomas, D.R.,Caporuscio, F.,Ciccarese, F.,Ghassabian, H.,Wagstaff, K.M.,Forwood, J.K.,Jans, D.A.,Palu, G.,Alvisi, G.; Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting.; Biochim Biophys Acta Mol Cell Res, 1865:1114-1129, 2018; PubMed: 29750988; DOI: 10.1016/j.bbamcr.2018.05.006

Experimental method

X-RAY DIFFRACTION (2.2 Å)