5KL7

Wilms Tumor Protein (WT1) ZnF2-4Q369R in complex with carboxylated DNA

Summary for 5KL7

• Entry DOI: 10.2210/pdb5kl7/pdb
• Related: 5KL2 5KL3 5KL4 5KL5 5KL6
• Descriptor: Wilms tumor protein, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(1CC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... (6 entities in total)
• Functional Keywords: wilms tumor protein, wt1, zinc finger, 5-carboxyl cytosine, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 18399.73

Authors

Hashimoto, H.,Cheng, X. (deposition date: 2016-06-23, release date: 2016-09-14, Last modification date: 2023-09-27)

• Primary citation: Hashimoto, H.,Zhang, X.,Zheng, Y.,Wilson, G.G.,Cheng, X.; Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications.; Nucleic Acids Res., 44:10165-10176, 2016; PubMed: 27596598; DOI: 10.1093/nar/gkw766

Experimental method

X-RAY DIFFRACTION (1.579 Å)