5KKB

Structure of mouse Golgi alpha-1,2-mannosidase IA and Man9GlcNAc2-PA complex

Summary for 5KKB

• Entry DOI: 10.2210/pdb5kkb/pdb
• Descriptor: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: alpha/alpha barrel, golgi apparatus, deglycosylation, glycan substrate analog, sugar binding protein
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 2
• Total formula weight: 111123.23

Authors

Xiang, Y.,Moremen, K.W. (deposition date: 2016-06-21, release date: 2016-12-07, Last modification date: 2020-07-29)

• Primary citation: Xiang, Y.,Karaveg, K.,Moremen, K.W.; Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.; Proc. Natl. Acad. Sci. U.S.A., 113:E7890-E7899, 2016; PubMed: 27856750; DOI: 10.1073/pnas.1611213113

Experimental method

X-RAY DIFFRACTION (1.774 Å)