5K5G

Structure of human islet amyloid polypeptide in complex with an engineered binding protein

Summary for 5K5G

• Entry DOI: 10.2210/pdb5k5g/pdb
• NMR Information: BMRB: 30099
• Descriptor: Islet amyloid polypeptide, HI18 (2 entities in total)
• Functional Keywords: hormone, amyloid, type 2 diabetes, beta-hairpin, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 19518.62

Authors

Mirecka, E.A.,Feuerstein, S.,Gremer, L.,Schroeder, G.F.,Stoldt, M.,Willbold, D.,Hoyer, W. (deposition date: 2016-05-23, release date: 2016-10-26, Last modification date: 2023-06-14)

• Primary citation: Mirecka, E.A.,Feuerstein, S.,Gremer, L.,Schroder, G.F.,Stoldt, M.,Willbold, D.,Hoyer, W.; beta-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor.; Sci Rep, 6:33474-33474, 2016; PubMed: 27641459; DOI: 10.1038/srep33474

Experimental method

SOLUTION NMR