5JXG

Structure of the unliganded form of the proprotein convertase furin.

Summary for 5JXG

Entry DOI	10.2210/pdb5jxg/pdb
Descriptor	Furin, CALCIUM ION, SODIUM ION, ... (5 entities in total)
Functional Keywords	protease, apo-structure, proteolysis, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein: P09958
Total number of polymer chains	1
Total formula weight	52728.21
Authors	Dahms, S.O.,Arciniega, M.,Steinmetzer, T.,Huber, R.,Than, M.E. (deposition date: 2016-05-13, release date: 2016-10-05, Last modification date: 2024-01-10)
Primary citation	Dahms, S.O.,Arciniega, M.,Steinmetzer, T.,Huber, R.,Than, M.E. Structure of the unliganded form of the proprotein convertase furin suggests activation by a substrate-induced mechanism. Proc.Natl.Acad.Sci.USA, 113:11196-11201, 2016 Cited by PubMed: 27647913 DOI: 10.1073/pnas.1613630113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation