5JTU

Crystal structure of GPb in complex with 8b

5JTU の概要

• エントリーDOI: 10.2210/pdb5jtu/pdb
• 分子名称: Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, (1S)-1,5-anhydro-1-[5-(naphthalen-2-yl)-1H-imidazol-2-yl]-D-glucitol, ... (5 entities in total)
• 機能のキーワード: alpha and beta protein transferase, transferase
• 由来する生物種: Oryctolagus cuniculus (Rabbit)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 98182.18

構造登録者

Kantsadi, A.L.,Stravodimos, G.A.,Chatzileontiadou, D.S.M.,Leonidas, D.D. (登録日: 2016-05-09, 公開日: 2016-08-24, 最終更新日: 2018-01-17)

• 主引用文献: Kantsadi, A.L.,Bokor, E.,Kun, S.,Stravodimos, G.A.,Chatzileontiadou, D.S.,Leonidas, D.D.,Juhasz-Toth, E.,Szakacs, A.,Batta, G.,Docsa, T.,Gergely, P.,Somsak, L.; Synthetic, enzyme kinetic, and protein crystallographic studies of C-beta-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.; Eur.J.Med.Chem., 123:737-745, 2016; PubMed: 27522507; DOI: 10.1016/j.ejmech.2016.06.049

実験手法

X-RAY DIFFRACTION (1.85 Å)