5JQT
Crystal structure of human carbonic anhydrase II in complex with Benzoxaborole at pH 7.4
Summary for 5JQT
| Entry DOI | 10.2210/pdb5jqt/pdb |
| Descriptor | Carbonic anhydrase 2, ZINC ION, 1,1-dihydroxy-1,3-dihydro-2,1-benzoxaborol-1-ium, ... (6 entities in total) |
| Functional Keywords | benzoxaborole, lyase, boron, zinc, carbonate dehydratase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 30904.05 |
| Authors | Alterio, V.,Esposito, D.,Di Fiore, A.,De Simone, G. (deposition date: 2016-05-05, release date: 2016-10-19, Last modification date: 2024-01-10) |
| Primary citation | Alterio, V.,Cadoni, R.,Esposito, D.,Vullo, D.,Fiore, A.D.,Monti, S.M.,Caporale, A.,Ruvo, M.,Sechi, M.,Dumy, P.,Supuran, C.T.,Simone, G.,Winum, J.Y. Benzoxaborole as a new chemotype for carbonic anhydrase inhibition. Chem.Commun.(Camb.), 52:11983-11986, 2016 Cited by PubMed: 27722534DOI: 10.1039/c6cc06399c PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.36 Å) |
Structure validation
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