5JIY

Structure of G9a SET-domain with Histone H3K9norLeucine mutant peptide and bound S-adenosylmethionine

Summary for 5JIY

Entry DOI	10.2210/pdb5jiy/pdb
Related	5JHN 5JIN 5JJ0
Descriptor	Histone-lysine N-methyltransferase EHMT2, Histone H3.1 mutant peptide with H3K9nor-leucine, ZINC ION, ... (5 entities in total)
Functional Keywords	set-domain, histone methyl transferase, histone peptide, transferase
Biological source	Homo sapiens (Human) More
Cellular location	Nucleus : Q96KQ7
Total number of polymer chains	4
Total formula weight	66886.45
Authors	Jayaram, H.,Bellon, S.F.,Poy, F. (deposition date: 2016-04-22, release date: 2016-09-14, Last modification date: 2023-11-15)
Primary citation	Jayaram, H.,Hoelper, D.,Jain, S.U.,Cantone, N.,Lundgren, S.M.,Poy, F.,Allis, C.D.,Cummings, R.,Bellon, S.,Lewis, P.W. S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3. Proc.Natl.Acad.Sci.USA, 113:6182-6187, 2016 Cited by PubMed: 27185940 DOI: 10.1073/pnas.1605523113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.48 Å)

Structure validation