5JH3

Human cathepsin K mutant C25S

Summary for 5JH3

Entry DOI	10.2210/pdb5jh3/pdb
Descriptor	Cathepsin K, SULFATE ION, ACETATE ION, ... (5 entities in total)
Functional Keywords	allostery cysteine, peptidase proteolysis, enzyme regulation, collagenase, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Lysosome: P43235
Total number of polymer chains	1
Total formula weight	24826.17
Authors	Novinec, M.,Korenc, M.,Lenarcic, B. (deposition date: 2016-04-20, release date: 2016-11-30, Last modification date: 2024-01-10)
Primary citation	Novinec, M.,Rebernik, M.,Lenarcic, B. An allosteric site enables fine-tuning of cathepsin K by diverse effectors. FEBS Lett., 590:4507-4518, 2016 Cited by PubMed: 27859061 DOI: 10.1002/1873-3468.12495 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation