5JDS

Crystal structure of PD-L1 complexed with a nanobody at 1.7 Angstron resolution

Summary for 5JDS

• Entry DOI: 10.2210/pdb5jds/pdb
• Descriptor: Nanobody, Programmed cell death 1 ligand 1, SODIUM ION, ... (6 entities in total)
• Functional Keywords: nanobody, immune system
• Biological source: Camelidae; More
• Cellular location: Isoform 1: Cell membrane ; Single-pass type I membrane protein . Isoform 2: Endomembrane system ; Single-pass type I membrane protein : Q9NZQ7
• Total number of polymer chains: 2
• Total formula weight: 30359.36

Authors

Zhou, A.,Wei, H. (deposition date: 2016-04-17, release date: 2017-04-12)

• Primary citation: Zhang, F.,Wei, H.,Wang, X.,Bai, Y.,Wang, P.,Wu, J.,Jiang, X.,Wang, Y.,Cai, H.,Xu, T.,Zhou, A.; Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade.; Cell Discov, 3:17004-17004, 2017; PubMed: 28280600; DOI: 10.1038/celldisc.2017.4

Experimental method

X-RAY DIFFRACTION (1.7 Å)