5JCP

RhoGAP domain of ARAP3 in complex with RhoA in the transition state

Summary for 5JCP

• Entry DOI: 10.2210/pdb5jcp/pdb
• Descriptor: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3,Linker,Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: rhoa, rhogap, arap3, signaling protein, hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane; Lipid-anchor; Cytoplasmic side: P61586
• Total number of polymer chains: 2
• Total formula weight: 95406.20

Authors

Bao, H.,Li, F.,Wang, C.,Wang, N.,Jiang, Y.,Tang, Y.,Wu, J.,Shi, Y. (deposition date: 2016-04-15, release date: 2016-06-22, Last modification date: 2023-11-08)

• Primary citation: Bao, H.,Li, F.,Wang, C.,Wang, N.,Jiang, Y.,Tang, Y.,Wu, J.,Shi, Y.; Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3; J.Biol.Chem., 291:16709-16719, 2016; PubMed: 27311713; DOI: 10.1074/jbc.M116.736140

Experimental method

X-RAY DIFFRACTION (2.1 Å)