5J7P

Macrophage Migration Inhibitory Factor bound to Covalent Inhibitor RDR03785

Summary for 5J7P

• Entry DOI: 10.2210/pdb5j7p/pdb
• Related: 5J7Q
• Descriptor: Macrophage migration inhibitory factor, 6-{[4-(trifluoromethyl)phenyl]methyl}-2H-1,3-benzodioxol-5-ol, SULFATE ION, ... (6 entities in total)
• Functional Keywords: isomerase, isomerase inhibitor, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted : P14174
• Total number of polymer chains: 3
• Total formula weight: 39022.80

Authors

Robertson, M.J.,Jorgensen, W.L. (deposition date: 2016-04-06, release date: 2016-05-04, Last modification date: 2023-09-27)

• Primary citation: Cisneros, J.A.,Robertson, M.J.,Valhondo, M.,Jorgensen, W.L.; Irregularities in enzyme assays: The case of macrophage migration inhibitory factor.; Bioorg.Med.Chem.Lett., 26:2764-2767, 2016; PubMed: 27156768; DOI: 10.1016/j.bmcl.2016.04.074

Experimental method

X-RAY DIFFRACTION (1.85 Å)