5J63

Crystal Structure of the N-terminal N-formyltransferase Domain (residues 1-306) of Escherichia coli Arna in Complex with UDP-Ara4N and Folinic Acid

Summary for 5J63

Entry DOI	10.2210/pdb5j63/pdb
Descriptor	Bifunctional polymyxin resistance protein ArnA, (2R,3R,4S,5S)-5-amino-3,4-dihydroxytetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, (4aS,6S)-2-amino-6-{(E)-[(4-methylphenyl)imino]methyl}-4-oxo-4,6,7,8-tetrahydropteridine-5(4aH)-carbaldehyde, ... (4 entities in total)
Functional Keywords	lipopolysaccharide, transferase
Biological source	Escherichia coli H736
Total number of polymer chains	4
Total formula weight	137503.56
Authors	Thoden, J.B.,Genthe, N.A.,Holden, H.M. (deposition date: 2016-04-04, release date: 2016-05-25, Last modification date: 2023-09-27)
Primary citation	Genthe, N.A.,Thoden, J.B.,Holden, H.M. Structure of the Escherichia coli ArnA N-formyltransferase domain in complex with N(5) -formyltetrahydrofolate and UDP-Ara4N. Protein Sci., 25:1555-1562, 2016 Cited by PubMed: 27171345 DOI: 10.1002/pro.2938 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation