5IZU

A new binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function

Summary for 5IZU

Entry DOI	10.2210/pdb5izu/pdb
Descriptor	SH3 and multiple ankyrin repeat domains protein 3, peptide from Disks large-associated protein 3 (3 entities in total)
Functional Keywords	shank, sapap, pdz, extension, synapse, specific interaction, protein binding
Biological source	Mus musculus (Mouse) More
Cellular location	Cytoplasm: Q4ACU6 Cell membrane ; Peripheral membrane protein : Q6PFD5
Total number of polymer chains	4
Total formula weight	34570.93
Authors	Shang, Y.,Zeng, M.,Zhang, M. (deposition date: 2016-03-26, release date: 2016-05-18, Last modification date: 2023-11-08)
Primary citation	Zeng, M.,Shang, Y.,Guo, T.,He, Q.,Yung, W.H.,Liu, K.,Zhang, M. A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function Proc.Natl.Acad.Sci.USA, 113:E3081-E3090, 2016 Cited by PubMed: 27185935 DOI: 10.1073/pnas.1523265113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.494 Å)

Structure validation