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5IX0

HDAC2 WITH LIGAND BRD7232

Summary for 5IX0
Entry DOI10.2210/pdb5ix0/pdb
Related5IWG
DescriptorHistone deacetylase 2, ZINC ION, CALCIUM ION, ... (10 entities in total)
Functional Keywordshdac histone deacetylase, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : Q92769
Total number of polymer chains3
Total formula weight131245.71
Authors
Steinbacher, S. (deposition date: 2016-03-23, release date: 2016-08-31, Last modification date: 2024-03-06)
Primary citationWagner, F.F.,Weiwer, M.,Steinbacher, S.,Schomburg, A.,Reinemer, P.,Gale, J.P.,Campbell, A.J.,Fisher, S.L.,Zhao, W.N.,Reis, S.A.,Hennig, K.M.,Thomas, M.,Muller, P.,Jefson, M.R.,Fass, D.M.,Haggarty, S.J.,Zhang, Y.L.,Holson, E.B.
Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors.
Bioorg.Med.Chem., 24:4008-4015, 2016
Cited by
PubMed: 27377864
DOI: 10.1016/j.bmc.2016.06.040
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.72 Å)
Structure validation

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