5IVX

Crystal Structure of B4.2.3 T-Cell Receptor and H2-Dd P18-I10 Complex

Summary for 5IVX

• Entry DOI: 10.2210/pdb5ivx/pdb
• Related: 5IW1
• Descriptor: H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, T-CELL RECEPTOR ALPHA CHAIN, ... (7 entities in total)
• Functional Keywords: major histompatibility complex class i, mhc-i, h2-dd, h-2dd, t-cell receptor, tcr, b4.2.3, b423, immune response, viral immunoevasion, immune system, human immunodeficiency virus, molecular recognition
• Biological source: Mus musculus (Mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01900; Secreted: P01887
• Total number of polymer chains: 5
• Total formula weight: 93877.44

Authors

Natarajan, K.,Jiang, J.,Margulies, D. (deposition date: 2016-03-21, release date: 2017-03-29, Last modification date: 2023-09-27)

• Primary citation: Natarajan, K.,McShan, A.C.,Jiang, J.,Kumirov, V.K.,Wang, R.,Zhao, H.,Schuck, P.,Tilahun, M.E.,Boyd, L.F.,Ying, J.,Bax, A.,Margulies, D.H.,Sgourakis, N.G.; An allosteric site in the T-cell receptor C beta domain plays a critical signalling role.; Nat Commun, 8:15260-15260, 2017; PubMed: 28508865; DOI: 10.1038/ncomms15260

Experimental method

X-RAY DIFFRACTION (2.1 Å)