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5IT3

Swirm domain of human Lsd1

Summary for 5IT3
Entry DOI10.2210/pdb5it3/pdb
DescriptorLysine-specific histone demethylase 1A, MAGNESIUM ION (3 entities in total)
Functional Keywordshelix, oxidoreductase
Biological sourceHomo sapiens (Human)
Cellular locationNucleus : O60341
Total number of polymer chains2
Total formula weight19919.21
Authors
Jeffrey, P.D.,Yuan, P. (deposition date: 2016-03-16, release date: 2016-05-18, Last modification date: 2024-03-20)
Primary citationHu, R.,Sun, X.,Hameed, U.F.S.,Moorthy, B.S.,Jeffrey, P.D.,Zhou, L.,Ma, X.,Chen, F.,Mu, Q.,Pei, J.,Swaminathan, K.,Yuan, P.
A Tlx-interacting peptide of Lsd1 inhibits the proliferation of brain tumor stem cells
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.4 Å)
Structure validation

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