5IR1

Cetuximab Fab in complex with 3-bromophenylalanine meditope variant

Summary for 5IR1

• Entry DOI: 10.2210/pdb5ir1/pdb
• Related: 5HPM 5HYQ 5I2I 5ICX 5ICY 5ICZ 5ID0 5ID1 5IOP
• Descriptor: Cetuximab Fab light chain, Cetuximab Fab heavy chain, Meditope variant, ... (6 entities in total)
• Functional Keywords: antibody, anti-egfr, immune system
• Biological source: MUS MUSCULUS, HOMO SAPIENS (mouse, human); More
• Total number of polymer chains: 6
• Total formula weight: 97546.45

Authors

Bzymek, K.P.,Williams, J.C. (deposition date: 2016-03-11, release date: 2016-10-26, Last modification date: 2023-09-27)

• Primary citation: Bzymek, K.P.,Avery, K.A.,Ma, Y.,Horne, D.A.,Williams, J.C.; Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.; Acta Crystallogr F Struct Biol Commun, 72:820-830, 2016; PubMed: 27834791; DOI: 10.1107/S2053230X16016149

Experimental method

X-RAY DIFFRACTION (2.482 Å)