5INN

Mouse Tdp2 D358N protein, apo state with increased disorder amongst variable DNA-binding grasp conformations

Summary for 5INN

Entry DOI	10.2210/pdb5inn/pdb
Related	4GZ1 5INK 5INL 5INM 5INO 5INP 5INQ
Descriptor	Tyrosyl-DNA phosphodiesterase 2, SULFATE ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	hydrolase, dna repair, endonuclease/exonuclease/phosphatase (eep) domain
Biological source	Mus musculus (Mouse)
Total number of polymer chains	5
Total formula weight	145068.48
Authors	Schellenberg, M.J.,Appel, C.D.,Williams, R.S. (deposition date: 2016-03-07, release date: 2016-04-27, Last modification date: 2023-09-27)
Primary citation	Schellenberg, M.J.,Perera, L.,Strom, C.N.,Waters, C.A.,Monian, B.,Appel, C.D.,Vilas, C.K.,Williams, J.G.,Ramsden, D.A.,Williams, R.S. Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res., 44:3829-3844, 2016 Cited by PubMed: 27060144 DOI: 10.1093/nar/gkw228 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation