5IL0

Crystal structural of the METTL3-METTL14 complex for N6-adenosine methylation

Summary for 5IL0

• Entry DOI: 10.2210/pdb5il0/pdb
• Related: 5IL1 5IL2
• Descriptor: METTL3, METTL14, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: methyltransferase, rna binding protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q86U44 Q9HCE5
• Total number of polymer chains: 2
• Total formula weight: 59425.55

Authors

Wang, X.,Guan, Z.,Zou, T.,Yin, P. (deposition date: 2016-03-04, release date: 2016-05-25, Last modification date: 2016-06-29)

• Primary citation: Wang, X.,Feng, J.,Xue, Y.,Guan, Z.,Zhang, D.,Liu, Z.,Gong, Z.,Wang, Q.,Huang, J.,Tang, C.,Zou, T.,Yin, P.; Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex; Nature, 534:575-578, 2016; PubMed: 27281194; DOI: 10.1038/nature18298

Experimental method

X-RAY DIFFRACTION (1.882 Å)